(n) an anti-inflammatory drug that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1; increases the risk of heart attacks, Example:Cox-2 inhibitors reduce the symptoms of arthritis without endangering the stomach and kidneys

coxcomb

(n) a conceited dandy who is overly impressed by his own accomplishments, Syn. cockscomb

coxsackievirus

(n) enterovirus causing a disease resembling poliomyelitis but without paralysis, Syn. Coxsackie virus

cox's orange pippin

(n) a yellow Pippin with distinctive flavor

coxswain

(n) the helmsman of a ship's boat or a racing crew, Syn. cox

rofecoxib

(n) a Cox-2 inhibitor (trade name Vioxx) that relieves pain and inflammation without harming the digestive tract; voluntarily withdrawn from the market in 2004, Syn. Vioxx

valdecoxib

(n) a Cox-2 inhibitor (trade name Bextra) that relieves pain and inflammation without harming the digestive tract, Syn. Bextra

belle isle cress

(n) of southwestern Europe; cultivated in Florida, Syn. Barbarea verna, American watercress, early winter cress, Barbarea praecox, American cress, land cress

cockscomb

(n) a cap worn by court jesters; adorned with a strip of red, Syn. coxcomb

comb

(n) the fleshy red crest on the head of the domestic fowl and other gallinaceous birds, Syn. coxcomb, cockscomb

cyclooxygenase

(n) either of two related enzymes that control the production of prostaglandins and are blocked by aspirin, Syn. Cox

cyclooxygenase-1

(n) an enzyme that regulates prostaglandins that are important for the health of the stomach lining and kidneys, Syn. Cox-1, Example:an unfortunate side effect of NSAIDs is that they block Cox-1

cyclooxygenase-2

(n) an enzyme that makes prostaglandins that cause inflammation and pain and fever, Syn. Cox-2, Example:the beneficial effects of NSAIDs result from their ability to block Cox-2

hip

(n) the ball-and-socket joint between the head of the femur and the acetabulum, Syn. hip joint, coxa, articulatio coxae

japan allspice

(n) deciduous Japanese shrub cultivated for its fragrant yellow flowers, Syn. winter sweet, Japanese allspice, Chimonanthus praecox

red-hot poker

(n) widely cultivated hybrid poker plant, Syn. Kniphofia praecox

schizophrenia

(n) any of several psychotic disorders characterized by distortions of reality and disturbances of thought and language and withdrawal from social contact, Syn. dementia praecox, schizophrenic psychosis, schizophrenic disorder

The Collaborative International Dictionary of English (GCIDE) v.0.53 Collaborative International Dictionary (GCIDE)

Cacoxenite

{ , n. [ Gr. kako`s bad + &unr_;&unr_;&unr_;&unr_;&unr_; guest. ] (Min.) A hydrous phosphate of iron occurring in yellow radiated tufts. The phosphorus seriously injures it as an iron ore. [ 1913 Webster ]

Cox

n. [ OE. cokes. Cf. Coax. ] A coxcomb; a simpleton; a gull. [ Obs. ] [ 1913 Webster ]

Go; you're a brainless cox, a toy, a fop. Beau. & Fl. [ 1913 Webster ]

Coxa

‖n. [ L., the hip. ] (Zool.) The first joint of the leg of an insect or crustacean. [ 1913 Webster ]

Coxalgy

{ ‖ } n. [ NL. coxalgia, fr. L. coxa hip. + Gr. &unr_;&unr_;&unr_; pain: cf. F. coxalgie. ] (Med.) Pain in the hip. [ 1913 Webster ]

Coxcomb

n. [ A corrupted spelling of cock's comb. ] 1. (a) A strip of red cloth notched like the comb of a cock, which licensed jesters formerly wore in their caps. (b) The cap itself. [ 1913 Webster ]

2. The top of the head, or the head itself. [ 1913 Webster ]

We will belabor you a little better,
And beat a little more care into your coxcombs. Beau & Fl. [ 1913 Webster ]

3. A vain, showy fellow; a conceited, silly man, fond of display; a superficial pretender to knowledge or accomplishments; a fop. [ 1913 Webster ]

Fond to be seen, she kept a bevy
Of powdered coxcombs at her levee. Goldsmith. [ 1913 Webster ]

Some are bewildered in the maze of schools,
And some made coxcombs, nature meant but fools. Pope. [ 1913 Webster ]

4. (Bot.) A name given to several plants of different genera, but particularly to Celosia cristata, or garden cockscomb. Same as Cockscomb. [ 1913 Webster ]

Coxcombical

a. Befitting or indicating a coxcomb; like a coxcomb; foppish; conceited. -- Cox*comb"ic*al*ly, adv. [1913 Webster]

Studded all over in coxcombical fashion with little brass nails. W. Irving. [1913 Webster]

Coxcombly

a. like a coxcomb. [ Obs. ] “You coxcombly ass, you!” Beau. & Fl. [ 1913 Webster ]

Coxcombry

n. The manners of a coxcomb; foppishness. [ 1913 Webster ]

Coxcomical

a. Coxcombical. [ R. ] [ 1913 Webster ]

Coxcomically

adv. Conceitedly. [ R. ] [ 1913 Webster ]

Coxswain

n. See Cockswain. [ 1913 Webster ]

Leucoxene

n. [ Leuco- + Gr. xe`nos stranger. ] (Min.) A nearly opaque white mineral, in part identical with titanite, observed in some igneous rocks as the result of the alteration of titanic iron. [ 1913 Webster ]

Phycoxanthine

{ } n. [ Gr. fy^kos seaweed + &unr_; yellow. ] A yellowish coloring matter found in certain algae. [ 1913 Webster ]

Princox

{ } n. [ Prim + cock. ] A coxcomb; a pert boy. [ Obs. ] [ 1913 Webster ]

rofecoxib

(Chem. & Med.) A chemical substance (C17H14O4S, molecular weight 314.36) used in medicine as an analgesic to alleviate pain and inflammation; it is a synthetic compound, and is marketed by Merck & Co. under the trade name Vioxx, in tablets giving dosages of 12.5 or 25 milligrams. It is classed as a non-steroidal anti-inflammatory drug (NSAID). Chemically, it is 4-[ 4-(methylsulfony)phenyl ]-3-phenyl-2(5H) furanone. Its chemical structure contains two phenyl rings and a furanone ring. It is believed to act by inhibition of prostaglandin biosynthesis, through inhibition of the enzyme cyclooxygenase-2 (COX-2); unlike aspirin, it does not inhibit cyclooxygenase-1. [ PJC ]