v. t. [ OE. twikken, originally the same word as twicchen; cf. LG. twikken. See Twitch. ] To pinch and pull with a sudden jerk and twist; to twitch; as, to tweak the nose. Shak. [ 1913 Webster ]
n. 1. A sharp pinch or jerk; a twist or twitch; as, a tweak of the nose. Swift. [ 1913 Webster ]
2. Trouble; distress; tweag. [ Obs. ] [ 1913 Webster ]
3. A prostitute. [ Obs. ] Brathwait. [ 1913 Webster ]