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a. 1. Exchanged; put in the place of another. [ 1913 Webster ]

2. (Chem.) Containing substitutions or replacements; having been subjected to the process of substitution, or having some of its parts replaced; as, alcohol is a substituted water; methyl amine is a substituted ammonia. [ 1913 Webster ]

Substituted executor (Law), an executor appointed to act in place of one removed or resigned. [ 1913 Webster ]